Josefina Scaglione (born 1987) is an Argentinian musical theatre actress, best known for her performance as Maria in the 2009 Broadway revival of West Side Story, for which she received a Tony nomination for Best Leading Actress in a Musical.
Scaglione was raised in Rosario, and became interested in performing as a child. While in high school, she received a scholarship to attend a summer arts program at Point Park University in Pittsburgh, Pennsylvania. Upon graduating from high school, Scaglione moved to Buenos Aires and began working as a musical theatre actress. In Buenos Aires, she performed in Cinderella, and as Amber Von Tussle in Hairspray.